Perchlorate mixed–ligand copper(II) complexes of β-diketone and ethylene diamine derivatives: Thermal, spectroscopic and biochemical studies

Abstract

The present work carried out a study on perchlorate mixed–ligand copper(II) complexes which have been synthesized from ethylenediamine derivatives ( 3a– c) and β-diketones. These complexes, namely [Cu(DA-Cl)(acac)H 2O]ClO 4 4, [Cu(DA-Cl)(bzac)H 2O]H 2O.ClO 4 5, [Cu(DA-OMe)(acac)H 2O]ClO 4 6, [Cu(DA-OMe)(bzac)H 2O]ClO 4 7, [Cu(DA-H)(acac)H 2O]2H 2O.ClO 4 8 and [Cu(DA-H)(bzac)H 2O]ClO 4 9 (where acac, acetylacetonate and bzac, benzoylacetonate) were characterized by elemental analysis, spectral (IR and UV–vis) and magnetic moment measurements. Thermal properties and decomposition kinetics of all complexes are investigated. The interpretation, mathematical analysis and evaluation of kinetic parameters ( E, A, Δ H, Δ S and Δ G) of all thermal decomposition stages have been evaluated using Coats–Redfern equation. The biochemical studies showed that, the diamines 3a– c have powerful effects on degradation of DNA and protein. The antibacterial screening demonstrated that, the diamine (DA-Cl), 3b has the maximum and broad activities against Gram +ve and Gram −ve bacterial strains.