Abstract
The present study shows that 28% of the myelinated and 27% of the unmyelinated axons in the L5 and S1 rat dorsal roots are immunolabeled for galanin. By contrast only 10% of the myelinated and 15% of the unmyelinated axons are immunolabeled for calcitonin gene-related peptide, which is the numerically predominant primary afferent peptide marker for dorsal root ganglion cells. Thus galanin, because of its presence in so many primary afferent fibers, emerges as an important primary afferent marker. In addition, since our data also show that galanin is present predominantly in unmyelinated and fine myelinated sensory axons, a hypothesis is that it is particularly concerned with the transmission of noxious information.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
