Abstract
The incidence ofpreeclampsia in Indonesia (1980-2001) was around 6-8% of the total pregnancies with maternal mortality rate 9.8-25%. In preeclampsia, an increase of apoptosis occurs as a result of a decrease ofBc1-2 expression before a pregnancy reached full term. The objectives of this study were to determine placental apoptosis index (AI) in preeclampsia and normal pregnancy, and its correlation with birth weight and mother's blood pressure. This study was an observational analytical study using cross sectional design among 63 patients consisted of32 preeclampsia and -31 normal pregnancies. This study was performed at Dr. Hasan Sadikin Hospital, during April-June 2008. Immunohistochemical analysis was used to examine the placental AI (caspase 3). Chi square test was used to analysed the result using p
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