PERAN LEMAK EPIKARDIAL PADA PENYAKIT JANTUNG KORONER STABIL

Ulzim Fajar,Mefri Yanni

doi:10.32883/hcj.v5i2.780

Abstract

<p><em>Visceral fat tissue widely known have endocrine function by secreting Cytokines that provide it function in metabolism of visceral organ such as heart. It function have pivotal role under physiology and patology condition by secreting antiinflamatory cytokines in physiology condition, otherwise proinflammatory cytokines in patology condition. Epicardial fat tissue as regard this function, have more important role to the heart, because it have two advantage than other visceral depots. First, this tissue have same microcirculation provided by small branch of coronary arteries, and second it were not boundary by any structure. Recent studies found that there were correlation between increased epicardial fat depot and coronary artery disease. It seems correlate with this unique structure and function. This literature review focuse on how is the role of epicardial fat tissue in atheroschlerotic process especially in coronary artery.</em></p>

Highlights

Jaringan lemak viseral sudah dikenal luas mensekresikan sitokin-sitokin yang berperan pada fungsi serta metabolisme organ viseral termasuk jantung
Visceral fat tissue widely known have endocrine function by secreting Cytokines that provide it function in metabolism of visceral organ
this tissue have same microcirculation provided by small branch of coronary arteries

Summary

JARINGAN LEMAK EPIKARDIAL Anatomi jaringan lemak sekitar jantung

Jaringan lemak epikardial adalah bagian dari jaringan lemak viseral yang berlokasi antara perikardium viseral dan miokardium, menyelimuti sekitar 80% permukaan jantung dan merupakan 20% dari total berat jantung (gambar 1).[4, 5]. Ada terminologi lain lemak yang berada disekitar jantung (table 1). Jaringan lemak viseral antara epikardial permukaan miokardium dan perikardial visceral. Jaringan lemak antara dua perikardial lapisan perikardial (perikardial viseral dan parietal)

Deposit lemak pada bagian

Faktor transkripsi diferensiasi lemak cokelat

PERAN PATOLOGIS JARINGAN LEMAK EPIKARDIAL PADA PENYAKIT JANTUNG KORONER

FAKTOR YANG MEMPENGARUHI DEPOSIT LEMAK EPIKARDIAL

Findings

TEORI PENYEBAB TERBENTUKNYA LEMAK EKTOPIK