Peptik ülser ve fonksiyonel dispepside ardışık tedavi ile yapılan Helicobacter pylorieradikasyonunun klinik etkisi

Abstract

Background and Aims: Helicobacter pylori infection plays an important role in the etiology of peptic ulcer and functional dyspepsia. Patients with peptic ulcer benefit from eradication of Helicobacter pylori, but there are fewer data related to this favorable response in patients with functional dyspepsia. In this study, we aimed to compare the benefit of sequential eradication therapy in patients with ulcer and non-ulcer dyspepsia who were diagnosed with Helicobacter pylori infection. Materials and Methods:166 patients were included in this study. Helicobacter pylori was checked via gastroscopic biopsy and rapid urease test. In all patients, the eradication status was checked by urea breath test in the 12 th week. Gastrointestinal symptom rating scale score was used to determine symptomatic improvement. Results:In the groups of ulcer and functional dyspepsia, a significant difference was determined in gastrointestinal symptom rating scale scores with sequential therapy (p