Peptide synthesis triggered by comet impacts: A possible method for peptide delivery to the early Earth and icy satellites

Abstract

We performed shock experiments simulating natural comet impacts in an attempt to examine the role that comet impacts play in peptide synthesis. In the present study, we selected a mixture of alanine (dl-alanine), water ice, and silicate (forsterite) to make a starting material for the experiments. The shock experiments were conducted under cryogenic conditions (77K), and the shock pressure range achieved in the experiments was 4.8–25.8GPa. The results show that alanine is oligomerized into peptides up to tripeptides due to the impact shock. The synthesized peptides were racemic, indicating that there was no enantioselective synthesis of peptides from racemic amino acids due to the impact shock. We also found that the yield of linear peptides was a magnitude higher than those of cyclic diketopiperazine. Furthermore, we estimated the amount of cometary-derived peptides to the early Earth based on two models (the Lunar Crating model and the Nice model) during the Late Heavy Bombardment (LHB) using our experimental data. The estimation based on the Lunar Crating model gave 3×109mol of dialanine, 4×107mol of trialanine, and 3×108mol of alanine-diketopiperazine. Those based on the Nice model, in which the main impactor of LHB is comets, gave 6×1010mol of dialanine, 1×109mol of trialanine, and 8×109mol of alanine-diketopiperazine. The estimated amounts were comparable to those originating from terrestrial sources (Cleaves, H.J., Aubrey, A.D., Bada, J.L. [2009]. Orig. Life Evol. Biosph. 39, 109–126). Our results indicate that comet impacts played an important role in chemical evolution as a supplier of linear peptides, which are important for further chemical evolution on the early Earth. Our study also highlights the importance of icy satellites, which were formed by comet accumulation, as prime targets for missions searching for extraterrestrial life.