Abstract
Since the inauguration of penicillin therapy, resistant early infectious cases have rarely been encountered. To our knowledge only 1 such case has been reported. 1 It is the purpose of this paper to present a case of penicillin-resistant early syphilis. REPORT OF A CASE A 24 year old Negro was admitted to the Dermatology and Syphilology section on Sept. 5, 1946 because of a penile lesion of six weeks' duration. After appearance of the lesion no treatment had been sought for three weeks. At that time the patient had received one intravenous injection of arsphenamine from a private physician, after which treatment the lesion became swollen and painful and did not heal. No further treatment was obtained until his entrance to the hospital. At admission, dark field examination revealed Treponema pallidum and Kahn and Wassermann tests of the blood elicited positive reactions; a diagnosis of primary syphilis was made,
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