Pediatric Hemophilia: A Study of Prevalence and Risk Factors in Nineveh Province

Abstract

Hemophilia is a severe, hereditary clotting factor deficiency. Pediatric hemophilia treatment requires a multidisciplinary approach. Hemophilia should be evaluated in the newborn period if there is exceptional bleeding or a positive family history. The current study sought to determine the prevalence of hemophilia causes in children in Nineveh province. Patient information was gathered, and hemophilia factor testing was done at Ibn Sina Teaching Hospital. This study included 254 children aged less than a year to ten years. All patients were clinically assessed, and factor testing was carried out using the Staco kits. Blood samples were collected between March 2021 and March 2023. Blood type was also determined for all trial participants. Factor F-VIII had the greatest infection rate (203), followed by vWF (34) and F-IX (15). A total of 22 children with both F-VIII and vWF were included. Hemophilia factors (F-VIII, F-VII, and vWF) are most prevalent during ages <1-4 years. Males had a higher incidence of hemophilia than females. Blood types O+, A+, and B+ had the greatest rates. A correlation at (P<0.05) was found between the F-XIII, F-VIII, and F-IX hemophilia factors and age groups. There are no substantial correlations between hemophilia factors and blood types. To reduce the number of cases, patients must be carefully followed up and treated, and the family's history must be tracked to avoid future infections.