PeCoP: automatic determination of persistently conserved positions in protein families.

Abstract

PeCoP is a WWW-based service which accepts a protein sequence, and reports positions that are conserved in close and distant sequence family members. The collation of family members is performed using iterative PSI-BLAST runs. Examining positional conservation in close and distant family members enables a better selection of positions that may play a role in determining the protein's structure and function. http://bioinformatics.org/pecop idoerg@burnham.org http://bioinformatics.org/pecop/about_pecop