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https://doi.org/10.1016/j.tetlet.2010.11.037
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Cite Journal: Tetrahedron Letters |  Publication Date: Nov 14, 2010 |
 Citations: 24 |
Affiliation: MSD (United States), University of Michigan–Ann Arbor
A mild, functional group tolerant palladium-catalyzed Negishi coupling of pyrazole triflates and nonaflates with alkyl, benzyl, and aryl zinc halides has been developed. It allows quick access to 3-substituted pyrazole analogs at late stage via common synthetic intermediates.
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