Abstract
Palladium-catalyzed carbonylative cross-methylation reactions of different chloroarene-Cr(CO) 3 complexes employing an intramolecularly stabilized dimethylindium (III) reagent have been studied. The coupling products (acetophenone derivatives) were isolated in 43-96% yield under standard reaction conditions (5 mol% PdCl 2 (PPh 3 ) 2 , 50 °C, 5 atm CO-pressure in THF). Also, carbonylative Suzuki-coupling reactions of phenylboronic acid with different chloroarene-Cr(CO) 3 complexes afforded the corresponding benzophenone derivatives in 48-78% yield under comparable conditions in the presence of potassium carbonate as a base.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
