PD5-04 CAN WE PREDICT WHICH PATIENTS WILL PRESENT RESOLUTION OF DETRUSOROVERACTIVITY (DO) AFTER TRANSURETHRAL RESECTION OF THE PROSTATE (TURP)?

Abstract

You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy & New Technology II1 Apr 2015PD5-04 CAN WE PREDICT WHICH PATIENTS WILL PRESENT RESOLUTION OF DETRUSOROVERACTIVITY (DO) AFTER TRANSURETHRAL RESECTION OF THE PROSTATE (TURP)? Alexandre Iscaife, Sabrina T. Reis, Aline Albertini, Marco A. Nunes, Antonio M. Lucon, Willian C. Nahas, Miguel Srougi, and Alberto A. Antunes Alexandre IscaifeAlexandre Iscaife More articles by this author , Sabrina T. ReisSabrina T. Reis More articles by this author , Aline AlbertiniAline Albertini More articles by this author , Marco A. NunesMarco A. Nunes More articles by this author , Antonio M. LuconAntonio M. Lucon More articles by this author , Willian C. NahasWillian C. Nahas More articles by this author , Miguel SrougiMiguel Srougi More articles by this author , and Alberto A. AntunesAlberto A. Antunes More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2015.02.303AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Detrusor overactivity (DO) is one of the most frequent consequences of bladder outlet obstruction (BOO) due to BPH. The aim of the present study is to determine which clinical and urodynamic variables may be related to the persistence of DO after transurethral resection of the prostate. METHODS Analysis of 46 patients with BOO due to BPH who underwent TURP from 2011 to 2012. All patients underwent urodynamic analysis pre and post operatively after 12 months. The clinical and urodynamic variables in the preoperative were correlated with the resolution of DO in the postoperative period. RESULTS Patients with DO in the preoperative period were older (65.2 vs 61.1 years; p = 0.041), had higher IPSS score (25.2 vs 19; p = 0.014) and higher maximum flow rates (8.6 vs 6.6 ml/s; p = 0.039). Patients who persisted with DO were statistically older than those with resolution (69 vs 63 years; p = 0.043 ng/ml). Among patients with a MCC under 250 ml, 63.6% persisted with DO against only 20% among those with a MCC over 250 ml (p = 0.024). Analyzing urodynamic variables together, we found that patients presenting a MCC < 250 ml and a amplitude of DO over 40 cmH2O resulted in a 66.7% chance of persistence of DO (p = 0.041). When the patient has these characteristics associated with an early DO, the chance of persistence of DO reached 83.3% (p = 0.013) (Table). CONCLUSIONS Advanced patient age together with a low MCC and an early and high amplitude of DO are the most important predictors for persistence of DO after relief of BOO. Analysis of urodynamic variables grouped as predictor of persistence of DO after TURP Resolution Persistence p Low MCC+High BCI absent 81.30% 18.8% 0.004 present 22.20% 77.80 Low MCC+High amplitude absent 75.00% 25.0% 0.041 present 33.30% 66.70% Low MCC+High amplitude+High BCI absent 76.50% 23.50% 0.014 present 25.00% 75.00% High amplitude+early DO absent 75.00% 25.00% 0.041 present 33.30% 66.70% Low MCC+high amplitude+early DO absent 73.70% 26.30% 0.013 present 16.70% 83.30% multiple and early DO absent 60.00% 40.00% 1.00 present 60.00% 40.00% © 2015 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 193Issue 4SApril 2015Page: e93 Advertisement Copyright & Permissions© 2015 by American Urological Association Education and Research, Inc.MetricsAuthor Information Alexandre Iscaife More articles by this author Sabrina T. Reis More articles by this author Aline Albertini More articles by this author Marco A. Nunes More articles by this author Antonio M. Lucon More articles by this author Willian C. Nahas More articles by this author Miguel Srougi More articles by this author Alberto A. Antunes More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...