PD48-07 FINAL VALIDATION OF A PATIENT REPORTED OUTCOME MEASURE (PROM) FOR PENILE CURVATURE SURGERY

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Peyronie's Disease (PD48)1 Sep 2021PD48-07 FINAL VALIDATION OF A PATIENT REPORTED OUTCOME MEASURE (PROM) FOR PENILE CURVATURE SURGERY Madhavi Natarajan, Deji Akiboye, Marta Skrodzka, Jade Harrison, Sylvia Yan, Eleni Anastasiadis, Pareeta Patel, Benjamin Ayres, and Nick Watkin Madhavi NatarajanMadhavi Natarajan More articles by this author , Deji AkiboyeDeji Akiboye More articles by this author , Marta SkrodzkaMarta Skrodzka More articles by this author , Jade HarrisonJade Harrison More articles by this author , Sylvia YanSylvia Yan More articles by this author , Eleni AnastasiadisEleni Anastasiadis More articles by this author , Pareeta PatelPareeta Patel More articles by this author , Benjamin AyresBenjamin Ayres More articles by this author , and Nick WatkinNick Watkin More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002070.07AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Patient reported outcome measures (PROM) in penile curvature surgery are poorly documented. Previous studies have developed questionnaires for use in alternative treatments (PDQ, IIEF) that do not account for subjective surgical outcomes. We have previously reported on a prospective study documenting the development of a PROM for use in penile curvature surgery. Here we report the final validation of the examined cohort. METHODS: All men being investigated for penile curvature surgery were eligible for assessment with the developed PROM. The developed PROM utilised a 4-domain structure with novel validated questions on penile appearance (PA), subjective pain and anxiety, erectile function and subjective overall bother. Non-validated questions were also included on general and sexual relationships. Cronbach's alpha was used to verify each domain reliably measured the same latent variable. Wilcoxon Signed Rank test was used to assess consistency between test and retest scores, and responsiveness to change between pre- and post-operative scores. Variability and bias were assessed using a Bland Altman plot. RESULTS: 202 men investigated for penile curvature surgery in a single centre were prospectively assessed using the developed PROM. Pre-operative PROM questionnaires were administered at first appointment and on day of surgery, with post-operative PROM administered at first follow up. All 202 men completed the baseline and retest pre-operative PROM, with 130 men to date completing the post-operative PROM. All questions had response rates >90%. Cronbach's alpha for Penile Appearance was 0.34 rising to 0.65 post operatively. Coefficients for pain subjectivity were 0.35. Cronbach's alpha coefficient for ED and bother scores were 0.87 and 0.77 respectively. Wilcoxon Signed Rank test for penile appearance and bother domains showed significant improvements post operatively (Penile appearance p=<0.00001, bother p=<0.00001) and pain pre-operatively (p=0.0006) with pain scores post operatively unaffected (P=>0.06). Variability remained consistent for increasing PA scores. CONCLUSIONS: The developed PROM shows content validity, construct validity and reliability for penile appearance, subjective pain, erectile function and overall subjective bother of penile curvature, with robust responsiveness to treatment. The final validated PROM is an effective adjunct to assessment of patients with penile curvature both before and after treatment. Source of Funding: NA © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e841-e841 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Madhavi Natarajan More articles by this author Deji Akiboye More articles by this author Marta Skrodzka More articles by this author Jade Harrison More articles by this author Sylvia Yan More articles by this author Eleni Anastasiadis More articles by this author Pareeta Patel More articles by this author Benjamin Ayres More articles by this author Nick Watkin More articles by this author Expand All Advertisement Loading ...