PD45-10 VALIDATION STUDY: PATIENT REPORTED OUTCOME MEASURE (PROM) FOR PENILE CURVATURE SURGERY.

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Peyronie’s Disease1 Apr 2016PD45-10 VALIDATION STUDY: PATIENT REPORTED OUTCOME MEASURE (PROM) FOR PENILE CURVATURE SURGERY. Angus Campbell, RIchard Akiboye, Saheel Mukhtar, Matthew Jackson, Tet Yap, and Nicholas Watkin Angus CampbellAngus Campbell More articles by this author , RIchard AkiboyeRIchard Akiboye More articles by this author , Saheel MukhtarSaheel Mukhtar More articles by this author , Matthew JacksonMatthew Jackson More articles by this author , Tet YapTet Yap More articles by this author , and Nicholas WatkinNicholas Watkin More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.2110AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES The subjective measures of successful penile curvature surgery are poorly defined. This study describes a PROM for baseline and post-operative assessment of patients with Peyronie’s disease (PD). METHODS Questions were selected following semi-structured interviews with PD patients. A multidisciplinary RAND consensus group of UK andrologists defined the item-specific PROM. The final construct domains were penile curvature (PC), erectile function (EF), sexual relationships and generic quality of life measure (GQoL). The draft PROM was piloted until a final version was agreed for this validation study. Over a 3-year period, all consecutive patients being considered for PD surgery were offered the PROM in one specialist centre. Internal consistency was assessed using Cronbach’s a to understand if construct domains reliably measured the same latent variable. Variability and bias was assessed using a Bland Altman plot. RESULTS The baseline PROM was self-completed pre-operatively in a test-retest fashion by 46 men. All questions had response rates >85%. Cronbach's alpha for the penile curvature construct was 0.78 ranging from 0.68 to 0.8 with any single item removed. Wilcoxon Signed Rank test for the penile curvature construct indicated no significant difference between the test and re-test scores (P<0.62). Variability remains consistent as average PC scores increase. Average differences between scores (bias) is small so future measurements should lie between the limits of agreement (+8 to -8) 95% CI. CONCLUSIONS The PC questions were answered consistently well and demonstrated content validity and reliability. To establish responsiveness, validity and generalisability of a PROM containing the most robust items from this analysis, deployment is required pre and post-operatively across healthcare providers. © 2016FiguresReferencesRelatedDetails Volume 195Issue 4SApril 2016Page: e1064 Advertisement Copyright & Permissions© 2016MetricsAuthor Information Angus Campbell More articles by this author RIchard Akiboye More articles by this author Saheel Mukhtar More articles by this author Matthew Jackson More articles by this author Tet Yap More articles by this author Nicholas Watkin More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...