PD48-08 PROSPECTIVE EVALUATION OF ERECTILE DYSFUNCTION WITH A VALIDATED PATIENT REPORTED OUTCOME MEASURE IN PATIENTS WITH PEYRONIE’S DISEASE REQUIRING NESBIT’S TYPE SURGERY

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Peyronie's Disease (PD48)1 Sep 2021PD48-08 PROSPECTIVE EVALUATION OF ERECTILE DYSFUNCTION WITH A VALIDATED PATIENT REPORTED OUTCOME MEASURE IN PATIENTS WITH PEYRONIE’S DISEASE REQUIRING NESBIT’S TYPE SURGERY Marta Skrodzka, Deji Akiboye, Jade Harrison, Sylvia Yan, Madhavi Natarajan, Eleni Anastasiadis, Pareeta Patel, Benjamin Ayres, and Nicholas Watkin Marta SkrodzkaMarta Skrodzka More articles by this author , Deji AkiboyeDeji Akiboye More articles by this author , Jade HarrisonJade Harrison More articles by this author , Sylvia YanSylvia Yan More articles by this author , Madhavi NatarajanMadhavi Natarajan More articles by this author , Eleni AnastasiadisEleni Anastasiadis More articles by this author , Pareeta PatelPareeta Patel More articles by this author , Benjamin AyresBenjamin Ayres More articles by this author , and Nicholas WatkinNicholas Watkin More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002070.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: There are very few prospective studies of the outcome of surgical intervention for Peyronie’s disease. In studies specifically reporting erectile dysfunction (ED), established tools used (including SHIM and IIEF) are not validated for Peyronie’s disease patients and can lead to erroneous results. We have previously published development of a validated PROM for Nesbit’s surgery measuring subjective outcomes. In this study we determined the rate and severity of ED pre and post-operatively. METHODS: 5 year prospective study of all patients recruited into a Peyronie’s PROM development. After a RAND consensus group of Peyronie’s patients and pilot PROM, a 4 question, 5 point (0-4) domain for erectile dysfunction was validated. Scores from 0 (no ED) to 16 (very severe ED) were recorded and stratified (mild ED – 5-8, moderate ED – 9-12, severe ED – 13-16) pre and post operatively. Exclusions: surgery for congenital curvature and grafts. Patients completed the PROM in clinic at time of decision for surgery, within a week pre-operatively, and 12 weeks post-Nesbit’s type surgery. RESULTS: 130 men underwent Nesbit surgery. Median age 57 years (25-73). 12 patients were excluded from the analysis for starting ED treatment in the preoperative period after the decision for surgery. Rates for no-, mild-, moderate- and severe ED were 47 (39.8%), 45 (38.1%), 23 (19.5%) and 3 (2.5%) out of 118 men. Post operatively, rates were 56 (47.5%), 43 (36.4%), 19 (16.1%) and 0 men. 93 men (78.8%) were on no treatment pre operatively and 79 men (66.9%) took no treatment for ED post operatively. 24 men (20.3%) were already on PDE5 treatment prior to presentation, with 38 men (32.2%) on tablet treatment post operatively. One patient who was on alprostadil injections pre-operatively remained on the same treatment post operatively. CONCLUSIONS: We report the first prospective assessment of ED in Peyronie’s surgery using validated PROM. Surgery did not result in deterioration of erectile function. High rates of pre-existing ED should be managed alongside surgery for a satisfactory patient outcome. Source of Funding: NA © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e841-e841 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Marta Skrodzka More articles by this author Deji Akiboye More articles by this author Jade Harrison More articles by this author Sylvia Yan More articles by this author Madhavi Natarajan More articles by this author Eleni Anastasiadis More articles by this author Pareeta Patel More articles by this author Benjamin Ayres More articles by this author Nicholas Watkin More articles by this author Expand All Advertisement Loading ...