PD44-01 ACCURACY OF ACTUAL STAGE PREDICTION USING VESICAL IMAGING-REPORTING AND DATA SYSTEM (VI-RADS) BEFORE RADICAL CYSTECTOMY FOR UROTHELIAL CARCINOMA

Abstract

You have accessJournal of UrologyCME1 Apr 2023PD44-01 ACCURACY OF ACTUAL STAGE PREDICTION USING VESICAL IMAGING-REPORTING AND DATA SYSTEM (VI-RADS) BEFORE RADICAL CYSTECTOMY FOR UROTHELIAL CARCINOMA Si Hyun Kim, Jang Hee Han, Seung-Hwan Jeong, Hyeong Dong Yuk, Chang Wook Jeong, Cheol Kwak, Hyeon Hoe Kim, and Ja Hyeon Ku Si Hyun KimSi Hyun Kim More articles by this author , Jang Hee HanJang Hee Han More articles by this author , Seung-Hwan JeongSeung-Hwan Jeong More articles by this author , Hyeong Dong YukHyeong Dong Yuk More articles by this author , Chang Wook JeongChang Wook Jeong More articles by this author , Cheol KwakCheol Kwak More articles by this author , Hyeon Hoe KimHyeon Hoe Kim More articles by this author , and Ja Hyeon KuJa Hyeon Ku More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003354.01AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Previous studies using the vesical imaging reporting and data system (VI-RADS) to predict muscle-invasive bladder cancer had some limitations. Most studies were performed with transurethral resection of bladder tumor specimens with few samples. This study was conducted to address these shortcomings and confirm the accuracy of VI-RADS for bladder cancer. METHODS: This study used data from the Seoul National University Prospectively Enrolled Registry for Urothelial Cancer–Radical Cystectomy (SUPER-UC-Cx). Patients who underwent multiparametric magnetic resonance imaging (mp-MRI) before radical cystectomy were included in this study between March 2020 and March 2022. All images were reported by radiologists and reviewed by two urologists. The patient characteristics and clinical information were blinded during the review. The performance of qualitative and quantitative variables in predicting muscle layer invasion or perivesical fat infiltration was verified by receiver operating characteristic (ROC) curve analysis. RESULTS: Of 208 patients, 182 (87.5%) underwent mp-MRI before radical cystectomy. Twenty-three patients with non-urothelial carcinoma, inappropriate MRI scans, and bladder filling were excluded. Cut-off for muscle invasion, VI-RADS score of 4 had the highest area under the curve (AUC) (sensitivity 0.84; specificity 0.93; accuracy 0.90; positive predictive value (PPV) 0.84; negative predictive value (NPV) 0.93, and AUC 0.88). Cut-off for perivesical fat invasion and VI-RADS score of 5 had the highest AUC (sensitivity, 0.78; specificity, 0.99; accuracy, 0.95; PPV, 0.96; NPV, 0.95; and AUC, 0.89). CONCLUSIONS: VI-RADS is a good predictor of bladder cancer staging before radical cystectomy and is especially helpful in predicting muscle invasion and perivesical fat infiltration. Source of Funding: None © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e1124 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Si Hyun Kim More articles by this author Jang Hee Han More articles by this author Seung-Hwan Jeong More articles by this author Hyeong Dong Yuk More articles by this author Chang Wook Jeong More articles by this author Cheol Kwak More articles by this author Hyeon Hoe Kim More articles by this author Ja Hyeon Ku More articles by this author Expand All Advertisement PDF downloadLoading ...