PD27-06 SHIFT WORK SLEEP DISORDER AND NIGHT SHIFT WORK SIGNIFICANTLY IMPAIR ERECTILE FUNCTION.

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation I1 Apr 2018PD27-06 SHIFT WORK SLEEP DISORDER AND NIGHT SHIFT WORK SIGNIFICANTLY IMPAIR ERECTILE FUNCTION. Katherine M. Rodriguez, Taylor P. Kohn, Jaden R. Kohn, E. Will Kirby, Stephen M. Pickett, Alexander W. Pastuszak, and Larry I. Lipshultz Katherine M. RodriguezKatherine M. Rodriguez More articles by this author , Taylor P. KohnTaylor P. Kohn More articles by this author , Jaden R. KohnJaden R. Kohn More articles by this author , E. Will KirbyE. Will Kirby More articles by this author , Stephen M. PickettStephen M. Pickett More articles by this author , Alexander W. PastuszakAlexander W. Pastuszak More articles by this author , and Larry I. LipshultzLarry I. Lipshultz More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.1357AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Non-standard shift workers, who regularly work hours outside a 7am-6pm workday, have been found to have worse general health when compared to men working standard shifts. Men working non-standard shifts are at increased risk for shift work sleep disorder (SWSD), a primary circadian rhythm disorder characterized by excessive daytime sleepiness associated with shift work. Here we examine the association between SWSD and erectile dysfunction (ED) in shift workers. METHODS Men presenting to a single andrology clinic between January 2014 - July 2017 completed validated questionnaires: IIEF, Patient Health Questionnaire (PHQ), and the SWSD Questionnaire. Men were also asked about shift work schedule, comorbidities, PDE5 inhibitor use, and testosterone use. Serum total testosterone values were determined for each visit. Linear regression was performed controlling for testosterone use, testosterone levels, PDE5-inhibitor use, age, and comorbidities to determine the effect of SWSD on erectile dysfunction as assessed using the IIEF-EF. RESULTS Of the 2,571 men completing questionnaires, 1,952 reported non-standard shift work and 196 were found to have SWSD. 802 men completed the IIEF-EF questionnaire. Non-standard shift work alone did not result in worse IIEF-EF scores (p = 0.31), but men with SWSD had IIEF-EF scores that were 2.8 points lower than men without SWSD (P<0.01). When assessing for the type of shift, we found that men who worked night shifts had IIEF-EF scores 7.58 points lower than men who worked during the day or evening (p < 0.01). Testosterone use improved IIEF-EF scores for men with SWSD by 2.90 points, ameliorating the effect of SWSD. Testosterone levels were not associated with worse erectile function. CONCLUSIONS Men with SWSD have statistically and clinically worse erectile function, and men who work night shifts have even worse ED. These findings suggest that circadian rhythm disturbance may significantly impact erectile function. Testosterone therapy may partly reverse the effects of SWSD. Shift work is a potential risk factor for ED and should be assessed for as part of the evaluation of men with ED. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e559 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Katherine M. Rodriguez More articles by this author Taylor P. Kohn More articles by this author Jaden R. Kohn More articles by this author E. Will Kirby More articles by this author Stephen M. Pickett More articles by this author Alexander W. Pastuszak More articles by this author Larry I. Lipshultz More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...