MP91-06 INCREASED RISK OF HYPOGONADAL SYMPTOMS IN SHIFT WORKERS WITH SHIFT WORK SLEEP DISORDER

Abstract

You have accessJournal of UrologySexual Function/Dysfunction: Medical, Hormonal & Non-surgical Therapy I1 Apr 2017MP91-06 INCREASED RISK OF HYPOGONADAL SYMPTOMS IN SHIFT WORKERS WITH SHIFT WORK SLEEP DISORDER Will Kirby, Adithya Balasubramanian, Javier Santiago, Mark Hockenberry, David Skutt, Taylor Kohn, Stephen Pickett, Asad Hasan, Alex Pastuszak, and Larry Lipshultz Will KirbyWill Kirby More articles by this author , Adithya BalasubramanianAdithya Balasubramanian More articles by this author , Javier SantiagoJavier Santiago More articles by this author , Mark HockenberryMark Hockenberry More articles by this author , David SkuttDavid Skutt More articles by this author , Taylor KohnTaylor Kohn More articles by this author , Stephen PickettStephen Pickett More articles by this author , Asad HasanAsad Hasan More articles by this author , Alex PastuszakAlex Pastuszak More articles by this author , and Larry LipshultzLarry Lipshultz More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.2846AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Non-standard shift workers, who regularly work hours outside a 7am-6pm workday, may have worse hypogonadal symptoms relative to daytime workers, and are also at increased risk for shift work sleep disorder (SWSD), a primary circadian rhythm disorder characterized by excessive daytime sleepiness associated with shift work. Here we examine the association between SWSD and hypogonadal symptoms in shift workers. METHODS Men presenting to a single andrology clinic between July 2014 - September 2016 completed questionnaires assessing shift work schedule, SWSD risk, and hypogonadal symptoms (quantitative Androgen Deficiency in the Aging Male (qADAM) questionnaire). The impact of non-standard shift work and SWSD on responses to qADAM was assessed utilizing ANOVA and linear regression. RESULTS Of the 2,487 men who completed the questionnaires, 766 (30.8%) reported working non-standard shifts in the past month. Of those, 282 (36.8%) were diagnosed with SWSD (Table 1). Controlling for age, comorbidities and testosterone (T) levels, non-standard shift workers had qADAM scores 0.8 points lower than daytime workers (p<0.01). Sub-group analysis of the non-standard shift workers showed that those with SWSD had qADAM scores 3.9 points lower than in men without SWSD (p<0.01). In this same sub-group analysis, SWSD was independently associated with lower testosterone (T) levels (mean decrease 100.4 ng/dL, p<0.01) when controlling for age, comorbidities and history of T supplementation. CONCLUSIONS Non-standard shift workers have more severe hypogonadal symptoms than daytime workers, and those non-standard shift workers with SWSD have even worse hypogonadal symptoms and lower T levels than those without. These findings suggest that poor sleep habits, as identified by SWSD, may contribute to the more severe hypogonadal symptoms seen in non-standard shift workers. © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e1220 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Will Kirby More articles by this author Adithya Balasubramanian More articles by this author Javier Santiago More articles by this author Mark Hockenberry More articles by this author David Skutt More articles by this author Taylor Kohn More articles by this author Stephen Pickett More articles by this author Asad Hasan More articles by this author Alex Pastuszak More articles by this author Larry Lipshultz More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...