Abstract
In the current study, firstly, a new pyrrole-based ligand (3,4-(ethylenedimercaptodiacetoxy)-N-(benzyl)-diethyl-2,5-pyrroledicarboxylate (L) was synthesized in the presence of diethyl-N-benzyl-3,4-dihydroxy-1H-pyrrole-2,5-dicarboxylate and 2,2'-(ethane-1,2-diylbis(sulfanediyl))diacetylchloride. Then, the palladium(II) complex of the synthesized ligand was obtained, and its structural features were examined by spectral (HRMS, ESI-MS, UV-Visible, FTIR, 1H NMR, 13C NMR, XRD-POWDER, SEM, EDX) and thermogravimetric (TG-DTA) techniques. The spectral and thermal measurements of the ligand and its Pd(II) complex show that the ligand is coordinated to the Pd2+ ion. Antimicrobial activities of both the ligand and its palladium complex were examined. It was determined that whereas the ligand indicated modest antimicrobial activity against Staphylococcus aureus and Candida albicans at a concentration of 6.25 µg/ml, the palladium complex was significantly effective against C. albicans at a concentration of 6.25 µg/ml.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
More From: Macedonian Journal of Chemistry and Chemical Engineering
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.