Abstract
Lobular carcinoma presents a diagnostic challenge. Imaging and clinical findings are usually subtle. In the current climate it imposes extra strain on our resources. Our aim was to assess contribution of MRI in the preoperative local staging of lobular and mixed lobular/ductal carcinoma and to evaluate whether we can select cases for preoperative MRI based on mammographic appearance.
Highlights
Previous research in this centre enabled the introduction of a local protocol of nonbiopsy and discharge of women
Mammography-detected cancers were luminal in 77% (P = 0.03), node negative in 77% (P = 0.005), with ductal carcinoma in situ (DCIS) in 81% (P = 0.007)
We applied our approach to 13 experienced readers assessing 13,694 screening mammograms from a large clinical study where women are categorised as high risk if they have a 5 to 8% 10-year risk computed by a validated risk model and their breast density is in the top decile of the study population
Summary
Previous research in this centre enabled the introduction of a local protocol of nonbiopsy and discharge of women
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