Abstract
IntroductionDermatofibrosarcoma protuberans is a rare low-grade soft tissue neoplasm with trunk and extremities being the most common sites of involvement. We report a rare case of male breast with dermatofibrosarcoma protuberans and its imaging features. To our knowledge the imaging appearance of dermatofibrosarcoma protuberans of the breast has never been reported in the literature.Case presentationWe report the imaging appearance of dermatofibrosarcoma protuberans on the breast of a 41-year-old Chinese man who initially presented with a palpable lump. A mammogram showed two lesions, one with well circumscribed and the other with an ill defined border, in his right breast. Conventional magnetic resonance imaging was performed and showed the well defined larger lesion with mild central hypointensity while the smaller lesion had an irregular border. Both lesions were well characterized on the fat-suppressed sequences.ConclusionsDermatofibrosarcoma protuberans is a rare soft tissue sarcoma and its occurrence on the breast is even rarer. Mammography and magnetic resonance imaging can help in characterizing the lesion and localizing the lesion for further diagnostic evaluation and surgical planning.
Highlights
Dermatofibrosarcoma protuberans is a rare low-grade soft tissue neoplasm with trunk and extremities being the most common sites of involvement
We report a rare case of male breast with dermatofibrosarcoma protuberans and its imaging features
Case presentation: We report the imaging appearance of dermatofibrosarcoma protuberans on the breast of a 41-year-old Chinese man who initially presented with a palpable lump
Summary
Dermatofibrosarcoma protuberans (DFSP) is a rare lowgrade soft tissue neoplasm that originates from the dermis and accounts for about 1.8% of all soft tissue sarcomas [1,2]. Journal of Medical Case Reports 2009, 3:8246 http://jmedicalcasereports.com/jmedicalcasereports/article/view/8246 dermatofibrosarcoma protuberans on the breast is rare. Diagnostic work-up comprised clinical examination, mammography and magnetic resonance imaging (MRI), and diagnosis was proved by both pathology and immunohistochemistry through surgical excision. To our knowledge, this is the first report of the imaging appearance of dermatofibrosarcoma protuberans of the breast. Mammography showed a subcutaneous oval mass with a smooth and sharp margin on his right breast, and another small oval mass with a less well-defined margin was seen adjacent to the main lesion (Figure 1). The larger lesion had a smooth contour and well defined borders on all sequences which, on T2weighted images, had a lower signal central region. Immunohistologic staining for vimentin and cluster of differentiation (CD) 34, negative for b-cell leukemialymphoma (Bcl -2), S-100 protein, smooth muscle actin (SMA), desmin and epithelial membrane antigen (EMA)
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