Abstract

Mesenchymal stem cells (MSC) represents a heterogeneous group of multipotent non-hematopoietic stem cells with self-renewal and differentiating into mesenchymal cell lineage. Recent studies have demonstrated that MSC has low immunogenicity, which means it does not express major histocompatibility complex (MHC) class Ⅱand other co-stimulating factors. Thus, due to the capability of anti-inflammatory and immunomodulatory effects, MSC therapy provides many possibilities for the treatment for immune skin diseases.

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