Pattern of Presentation of Pseudo Exfoliation Deposits on the Lens Capsule in a Tertiary Eye Hospital in Dhaka, Bangladesh

Abstract

Objective: To assess the pattern of ocular presentation in patients with pseudoexfoliation syndrome and pseudoexfoliation glaucoma in Ispahani Islamia Eye Institute and Hospital, Dhaka, Bangladesh. Methods: This prospective observational study was conducted over 6 months in a glaucoma department of a tertiary eye institute in Bangladesh. All patients diagnosed with pseudoexfoliation glaucoma and pseudoexfoliation syndrome were recruited for the study. Clinical and demographic variables, pattern of presentation of pseudoexfoliation glaucoma and pseudoexfoliation syndrome, location of pseudoexfoliation deposit on the lens surface, and pupillary abnormalities observed with slit lamp examination were analyzed. Results A total of 46 eyes of 27 patients with pseudoexfoliation deposit were studied. There were 24 (88.9%) males and the mean age of the patients was 67.0 (±10.8) years. There was peripheral ring of pseudoexfoliation deposit observed on the anterior lens capsule of 12 eyes (n = 12 eyes). However, pseudoexfoliation deposits on the pupillary ruff were the most common pattern of presentation (n = 42 eyes). Poor pupillary dilation was observed in only one eye (n = 1 eye). Open-angle glaucoma was the commonest glaucoma (96.3%) associated with pseudoexfoliation syndrome and the patients had baseline intraocular pressure on the right and left eyes of 22.7 (±12.7) mmHg and 17.5 (±8.0) mmHg, respectively. Bilateral pseudoexfoliation was the most common presentation among patients with pseudoexfoliation glaucoma (n = 20). Conclusion Peripheral ring of pseudoexfoliation deposit was the classical deposit on the anterior lens capsule, whereas the central disk was absent in most cases. Poor pupillary dilation was rare.