Abstract

19650 Background: Information regarding pattern of malignancies in geriatric patients in India is not readily available. Methods: Between 1st January 1999 and 31st December 2006 we encountered 832 geriatric patients among a total of 3748 cases. Analysis was done with respect to age, sex and disease. Results: Geriatric patients constituted 832/3748 (22.20%) of our work load. Males 432 (51.92%) Females 400 (48.08%). Hematologic malignancies 214 (25.72%) Solid tumors 618 (74.28%). male preponderance in Hematologic malignancies 141/214 (66.89%); female preponderance in solid tumors 327/618 (52.91%). Top 7 malignancies: Males (432)-NSCLC 60 (13.89%) Prostate 57 (13.19%) NHL 48 (11.11%) Myeloma 39 (9.03%) CLL 31 (7.18%) HNSCC 30 (6.94%) Colon 26 (6.02%); Females (400)- Breast 147 (36.75%) Ovary 50 (12.50%) Uterus 44 (11.00%) NHL 25 (6.25%) Colon 20 (5.00%) NSCLC 11 (2.75%) CML 10 (2.50%). Age groups: (65–70) yrs-517 (62.13%) males 254, females 263; (71–80) yrs-264 (31.73%) males 152 females 112; (81–90) yrs-48 (5.78%) males 24, females 24; >91yrs-3 (0.36%) males 2 female 1. Top 5 malignancies in each age & sex group: Males, (65–70) yrs, 254: NSCLC 39 NHL 30 Prostate 29 Myeloma 24 Colon 19; (71–80) yrs, 152: Prostate 20 NSCLC 19 NHL 17 CLL 15 HNSCC 14; (81–90) yrs, 24: Prostate 7 Myeloma 2 CLL 2 CML 2 AML 2; Females, (65–70) yrs, 263: Breast 99 Ovary 37 Uterus 30 colon 13 NHL 13; (71–80) yrs, 112: Breast 41 Ovary 12 NHL 11 Uterus 10 CLL 9; (81–90) yrs, 24: Breast 7 Uterus 4 CLL 2 Renal cell carcinoma 2 Ovary 1. Conclusions: Solid tumors are the predominant malignancies in geriatric patients 618/832 (74.28%). B Cell neoplasms constitute bulk of the hematologic neoplasms 173/214 (80.84%). Sarcomas are uncommon 20/832 (2.40%). Important solid tumors: Prostate, NSCLC, Colon and HNSCC in males; Breast, Ovary, Uterus and colon in females. Age group (65–70) yrs is the major group 517/832 (62.13%) followed by significant age group (71–80) yrs 264/832 (31.73%). It is imperative to employ curative strategies for malignancies in this ever expanding population. No significant financial relationships to disclose.

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