Abstract
Background: Serum glutamic pyruvic transaminase (SGPT) and Serum glutamic oxaloacetic transaminase (SGOT) are the liver transaminases. Nowadays, there is intensified interest in studying the role of liver transaminases in independently predicting cardiac-related morbidity and mortality. In recent years, coronary heart disease has increased to an alarming rate throughout the world including Bangladesh. There are several mechanisms by which liver enzymes including SGPT, SGOT, and ALP are raised following ST-segment elevation myocardial infarction (STEMI). Few studies have demonstrated that gamma-glutamyltransferase (GGT), lactate dehydrogenase (LDH) and alkaline phosphate (ALP) are also increased in patients with acute myocardial infarction. We have studied the associations of liver enzymes change due to ST-segment elevation myocardial infarction (STEMI). Aims and Objectives: To observe the pattern of liver enzymes change among the ST elevation MI (STEMI) patients in the hospitalized patients and to associate the changes to outcomes of the patients. Study design and study setting: This was a hospital based prospective observational study conducted in the Department of Cardiology, Comilla Medical College & Hospital, Cumilla, during the period from January 2021 to June 2021. Methods: 100 randomly selected patients hospitalized in the Cardiology Department of the Comilla Medical College & Hospital from January 2021 to June 2021 with Acute ST elevation MI (STEMI) was enrolled in the study. All patient’s history and clinical examination was done and demographic variables was noted in the “Data collection sheet”. We had study the liver enzymes change at the baseline day 1 and at 6th day and note all the clinical and laboratory parameters. Data was analyzed using SPSS 24 version. Values of p<0.05 was considered statistically significant. Results: The mean (+SD) age of the patients was 56.06±12.016. The peak age incidence of STEMI was found in 55 to 64 years’ age group (37%).
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