A Comparative Study of Clinical and Angiographic Profile of Acute Stemi Patients in Age Group of Below and Above 40 Years in South Indian Population

Abstract

Background: ACS-STEMI in young adults may have some characteristics such clinical, novel CVRF’s & angiographic proile that are different from those in older patients. Objective: To assess the frequency, risk factors, presenting symptoms, treatment in-hospital outcomes of young patients with STEMI compared with those of older patients Material and Method: The present study had 242 cases of acute ST elevation MI of both the sex, aged below and above 40 years treated in Cardiology department. Risk factors including hsCRP, Lp(a) and homocystiene; presenting symptoms, in two age groups were analyzed. Results: Acute ST elevation MI patients in age group below 40 years were 18.6% and in above 40 years age group were 81.4%. Overall mean age of presentation of STEMI is 54.31 years. STEMI was more common in younger age group 88.9% than in older age group 76.6%. STEMI was more common in male (78.9%) than female (21.1%). Overall most common symptom was breathlessness (72.3%), in younger age group chest pain was common (71.1%). The prevalence of hypertension and DM much or less equally distributed in both age groups. Prevalence of smoking in younger age group was 64.4% and in older age group 53.3%. A family history of CAD in younger age group was 35.6% and in older age group 24.9%. Lipoprotein (a) level was higher in younger age group which is statistically significant. hsCRP levels was increased above the normal range in older age group patients which was statistically significant. Conclusion: Acute ST elevation MI patients in age group below 40 years were 18.6% and in above 40 years age group were 81.4%. Acute STEMI was more common in male than female. Most common symptom was breathlessness. Lipoprotein (a) was significantly higher in younger age group; hsCRP was significantly higher in older age group.