Abstract
Background: India is experiencing a rapid health transition and is projected to become a major reservoir of chronic diseases like diabetes and hypertension and 2540% of these subjects may develop chronic kidney disease (CKD) and end stage renal disease (ESRD)Objectives: To analyse the drug utilisation pattern of antihypertensives in patients with Chronic Kidney Disease.Materials and Methods: A cross sectional study conducted in patients with Chronic Kidney Disease in a tertiary care hospital over a period of 6 months in 2014. The information regarding demographic details and antihypertensive drugs prescribed were collected from the patients case records and the data was compiled and subjected to statistical analysisResults: Total of 95 case records was analyzed. CKD was more common in males, with male to female ratio of 4:1. 49.47% of the patients belonged to the age group of 40 60 years followed by 31 40 years (26.32%). Among the antihypertensives calcium channel blockers, diuretics, centrally acting antihypertensives, ? blockers, ? blockers, vasodilators, ?+? blockers and ACE inhibitors were routinely used.
Highlights
Chronic kidney disease (CKD) is a worldwide health problem, with adverse outcomes of kidney failure, cardiovascular disease (CVD) and premature death.[1]
Inpatients that came for dialysis and diagnosed of having Chronic Kidney Disease by the consultant Nephrologist according to KDOQI guidelines were included
Chronic kidney disease is defined as either kidney damage or a decreased glomerular filtration rate of less than 60 mL/min/1.73 m2 for 3 or more months by the Kidney Disease Outcomes Quality Initiative (K/DOQI) of the National Kidney Foundation (NKF).[7]
Summary
Chronic kidney disease (CKD) is a worldwide health problem, with adverse outcomes of kidney failure, cardiovascular disease (CVD) and premature death.[1]. CKD patients receive nearly 10 to 12 medications daily, many of which require multiple doses every day and due to this, frequent medication adjustments are required.[5] Prescribing pattern studies can provide useful information for the improvement of appropriate and effective use of drugs in a hospital. This will have an enormous impact on patient’s quality of life and contribute substantially to the financial cost of patient care.[6].
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