Abstract
The taxonomic composition and microbiota population level in the colon cavity content of the 95 patients with diarrheal escherichiosis and 87 healthy individuals were investigated. The acute diarrheal escherichiosis develops against the background of taxonomic composition and bacterial population disorders of autochthonous obligate anaerobic gram-positive microbiota (Bifidobacterium and Lactobacillus), with a growing number of bacterial genera Bacteroides, Peptostreptococcus, Clostridium and facultative anaerobic and aerobic bacteria of the genus Escherichia, Proteus, Staphylococcus and fungi genus Candida, contamination and colonization of colon cavity conditionally pathogenic enterobacteria (Citrobacter, Enterobacter, Proteus, etc.) Peptococcus, fungi genus Candida, and the growth and proliferation of Enteropathogenic, Enteroinvasive, Enterohemorrhagic Escherichia coli and Hemolytic (E. coli Hly +) and lactose-negative E. coli. Dysbacteriosis was diagnosed in 57,89 % patients with acute enterocolitis, dysbiosis available in 42,11 %. Among them, 63,16 % subjects had dysbiosis 3rd and 4th degrees, 36,84 % – dysbiosis 1st and 2nd degrees (c2=13,16; p<0,001). Among healthy individuals Normal flora subjects dominate over those with 1st and 2nd degree dysbiosis (89,66 % vs. 10,34 %, p<0,001).
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