Abstract

A mathematical model was applied to the hematopoietic reconstitution study of a group of thirteen patients with Hodgkin and Non-Hodgkin Lymphoma after having undergone Autologous Transplantation of Hematopoietic Progenitors in the Hematology Service of the Surgical Clinical University Hospital "Arnaldo Malian". Based on the model, the recovery process dynamics were computationally simulated, and the hematopoietic recovery times of each patient collected in the clinical data were compared with the times predicted by the simulations. Despite the simplicity of the mathematical model, it is surprising how well the reconstitution curves coincide with the clinical data collected, in such a manner that the model is able to predict with acceptable accuracy when hematopoietic recovery occurs. Model forecasts can be used to estimate the average duration of the pre-implant transplant and the next, which, in turn, will increase the number of patients benefited by this procedure.

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