Abstract
Objective: To compare test acceptability and compliance of two surveillance strategies in a high-risk group of women who were all BRCA mutation carriers over a 23-month follow-up period, (1) a new surveillance strategy based on assessment of serum CA-125 and HE4 every 4 months using a Risk of Ovarian Cancer Algorithm (ROCA) and (2) standard of care (SOC) surveillance with a CA-125 blood test and a pelvic ultrasound examination every 6 months were conducted.
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