Abstract
Summary Pathways of glucose utilization in epididymal and testicular sperm cells were investigated, using C 14 -labeled glucose as a tracer. An equal contribution to CO 2 from the two substrates in epididymal spermatozoa, and a preferential recovery of CO 2 from glucose-1-C 14 , as compared with glucose-6-C 14 in testicular sperm cells, were observed. Results suggest that in epididymal spermatozoa the basic mechanism of glucose utilization is that of the Embden-Meyerhof scheme; whereas, in the testicular sperm cells, glucose may be metabolized via alternative pathways.
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