Abstract
Cardiac magnetic resonance (CMR) imaging is useful tool for evaluation of histopathology and cardiac function in myocardial disease. We compared imaging of CMR with endomyocardial biopsy (EMB) in non-ischemic cardiac disease. We retrospectively analyzed 28 patients (8 female, mean age 49±17) who underwent CMR and EMB between October, 2009 and March, 2014. Diffuse thinning of left ventricular wall was found in 6 cases and hypertrophy was found in 9 cases. Late gadolinium enhancement imaging (LGE) was clearly detected in 8 cases from CMR imaging. In EBM, severe fibrotic change was detected in 10 cases and myocyte swelling was found in 12 cases, whereas nucleus condensation was found in 20 cases. Five cases, clinically diagnosed as cardiac sarcoidosis and demonstrated typical pattern of LGE, failed to detect sarcoid nodule by EMB. Two cases of amyloid heart diseases with typical pattern of LGE also failed to detect amyloid infiltration by EMB. Cardiac magnetic resonance imaging gives us additive and complementary information beyond EMB.
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