Pathogens of bovine mastitis and their sensitivity to antimicrobials

Abstract

Mastitis is the most important disease in the dairy industry. Antibiotics are considered to be the first choice in the treatment of the disease. However, the problem of antibiotic residue and antimicrobial resistance, leads to many restrictions on antibiotic therapy in the dairy sector worldwide.The work is devoted to the study and analysis of the sensitivity of pathogens of acute mastitis in cows to different antibacterial drugs. Bacteriological studies were carried out according to the generally accepted methods. Antibiotic sensitivity was determined by the disk diffusion method.The dynamics of isolation of the main pathogens of acute mastitis in cows and their antibiotic sensitivity within a 5-year period (2017-2021) in the central region of Russia was analyzed. It has been established that in recent years gram-positive infections became predominant, while coagulase-negative staphylococci are increasingly replacing S. aureus. Representatives of the genus Enterococcus were predominant causative agents of the disease. High-level multidrug resistance of all isolated strains of pathogens was determined (97%).The improvement of laboratory diagnosis and strict control over the use of antimicrobials need to reduce the level of resistance and the spread of multi-resistant pathogens of pyo-inflammatory diseases.