Pathogen distribution and resistance analysis of elderly patients with pulmonary infection

Abstract

Objective Through To analyzing analyze the pathogen distribution and resistance analysis of elderly patients with pulmonary infection, in order to provide basis for clinical rational administration. Methods The clinical data of 285 elderly patients diagnosed as pulmonary infection were selected, and their sputum specimens cultivation were collected for statistical analysis, and the pathogenic bacteria distribution and drug resistance were analyzed. Results 292 strains of pathogenic bacteria were detected from 285 patients, of which 204 strains of gram-negative bacteria, accounting for 69.8%, mainly including pseudomonas aeruginosa, acinetobacter baumannii and klebsiella pneumoniae, while 84 strains of gram-positive bacteria, accounting for 28.8%, mainly including staphylococcus aureus and 4 strains of fungus, accounting for 1.4%.Different pathogens showed different degrees of antimicrobial resistance: pseudomonas aeruginosa, acinetobacter baumannii, klebsiella pneumoniae and e. coli had highly sensitivity for imipenem and meropenem, which were secondly sensitive to amikacin and highly resistant to ampicillin; Staphylococcus aureus and epidermis staphylococcus were all sensitive to linezolid and vancomycin, which were highly resistant to benzyl penicillin. Conclusion Gram-negative bacilli is the main bacteria for patients with pulmonary infection, which has higher antimicrobial drug resistant rate, and antimicrobial agents should be rationally used according to drug susceptibility results. Key words: Pneumonia; Pathogen; Resistance; Aged