Abstract
When a cell dies in vivo the innate immune system investigates the scene of the crime. If the death of the cell is physiological, e.g. as part of normal cell turn over, then the corpse is cleared and little else is done. In fact, as part of this process phagocytes that ingest normal apoptotic cells can actively suppress tissue responses by elaborating anti-inflammatory cytokines (1). However, if the cell has died unexpectedly from some pathological process, then the innate immune system expands its investigation.
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