Abstract
Abstract With millions of nucleic acid (NA) and amino acid (AA) sequences produced so far, the task of identifying and tracking those sequences that are disclosed in patents has become increasingly challenging. Over 15 million sequences have been published and about 5% of the total NA sequences and 29% of AA sequences have been patented or are under patenting process worldwide (as of August 2001). This article brings together information on three major databases in this field, both public and commercial, that make such patent information available to the scientific community. The public effort is represented by the GenBank®/Entrez system and its collaborating partners. The commercial systems are led by Chemical Abstract Service (CAS) and Derwent with their corresponding databases CAS Registry and Derwent GENESEQ. GenBank®, GENESEQ and Registry all vary in their patent coverage. The article concludes that no single database possesses the inclusive collection of patent sequences, and therefore a combination of searches in these three major databases is needed for comprehensive access to the fast growing worldwide disclosures of NA and AA sequences in patents.
Published Version
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