Abstract
The emergence of patent medicines and so called "domestic medicines" could be traced trough different advertisements that appeared in Serbia during the second half of the 19th century. Most of those drugs were imported from abroad without any official control. The new patent medicines explosions, which began with the rising of domestic chemical and pharmaceutical laboratories for industrial compounding and selling medicines, rushed an urgent need to introduce some statutory provisions regulating the matter. Due to enormous advertising in the papers the patent medicines were very popular and widely spread.
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