Abstract
Assessment of glucose concentration is vital for diagnosis and treatment of diabetes mellitus. Since the electrochemical advantages of diamond for biosensing, we introduced partly-oxygen-diamond solution-gate field-effect transistor (SGFET) to detect glucose. Partly-O-diamond was obtained from H-diamond by ultraviolet ozone treatment. Then, 1-pyrenebutyric acid–N-hydroxy succinimide ester and glucose oxidase were modified on diamond surface. At last, shifts of transfer characteristics were applied to determine glucose concentration. The as-prepared biosensor exhibited a wide linear response from 10−5 to 10−1 M with high sensitivity of −53 mV/log10 [glucose concentration]. Furthermore, this biosensor showed good repeatability and stability in multiple detections.
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