Abstract

Peritoneal washings from normal mice, or the cell-free Supernatants, and fibrinogen preparations of human and murine origin were alike in their ability to aggregate carbon in indian ink, polystyrene latex, colloidal metal oxides, and solutions of certain dyes.Peritoneal fluid tended first to develop and then to lose the power to aggregate suitable materials on standing at room temperature; fibrinolytic digestion of carbon aggregated by peritoneal fluid or by fibrinogen released products with the serological specificity of fibrinogen. Intermediate products in the degradation of fibrinogen appeared to be the aggregating factor in mouse peritoneal fluid in vitro .

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