Abstract
A quantitative ultrastructural investigation of cancer in mice mammary glands and of its metastases to the lungs was carried out. It was established that in tumors showing no metastatic spreading in experiment the area of membrane surface of the endoplasmic reticulum and the number of bound ribosomes are greater than those in tumor spreading metastases. At the same time the number of ribosomes organized into polysomes is higher in the metastasized tumors. The comparison of the tumors with their metastases revealed differences in the structure of the mitochondrial apparatus: the surface area of cristae is larger in the metastatic foci. The evidence obtained shows that tumors spreading metastases have a lower level of cellular differentiation. The primary and metastatic foci do not exhibit any difference in the level of differentiation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
