Abstract
Oncocytosis is a rare, benign, non-neoplastic lesion that can be further classified into diffuse oncocytosis or multifocal adenomatous oncocytic hyperplasia. This tumour has been estimated to account for 0.1% of all parotid gland tumours.1 Here, we report a rare case of a patient who presented to the Oral and Maxillofacial Surgery Department with a 3-cm swelling of his left parotid gland. Histopathological results from a superficial parotidectomy revealed the lesion to be a multifocal adenomatous oncocytic hyperplasia of the parotid gland. A description of this rare disease and its management are included in this article.
Highlights
Singapore Dental JournalSingapore Dent J 2019.39:63-68. Downloaded from www.worldscientific.com by 54.85.206.46 on 11/08/21. Re-use and distribution is strictly not permitted, except for Open Access articles. Parotid gland oncocytosis: Multifocal adenomatous oncocytic hyperplasia variant — A case report in Singapore Chee Seng Lee*, Eugene Hze-Khoong Poh†, Venkateswaran Kotamma‡, Tsu Ken Loy§, Hsun Tau Chow¶ Keywords: Parotid gland Oncocytosis Multifocal adenomatous oncocytic hyperplasia Salivary gland tumours
Oncocytes are epithelial cells with abundant, granular, eosinophilic cytoplasm and a central pyknotic nucleus packed with mitochondria
They were first described by Shaffer in 18972 and further characterised by Hamperl in 1931.3 Oncocytes have been observed in the salivary glands, thyroid, parathyroid, pituitary gland, nasal cavities, sinuses, ocular caruncle, lacrimal glands, buccal mucosa, eustachian tube, larynx, oesophagus, liver, pancreas, and kidneys,[4] and they range in presentation from hyperplasia to malignancy
Summary
Singapore Dent J 2019.39:63-68. Downloaded from www.worldscientific.com by 54.85.206.46 on 11/08/21. Re-use and distribution is strictly not permitted, except for Open Access articles. Parotid gland oncocytosis: Multifocal adenomatous oncocytic hyperplasia variant — A case report in Singapore Chee Seng Lee*, Eugene Hze-Khoong Poh†, Venkateswaran Kotamma‡, Tsu Ken Loy§, Hsun Tau Chow¶ Keywords: Parotid gland Oncocytosis Multifocal adenomatous oncocytic hyperplasia Salivary gland tumours
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