Abstract
Acquired hepatocerebral degeneration is a heterogeneous neurological disorder resulting from chronic liver disease. Neuropsychiatric, cerebellar and extrapyramidal findings in different combinations may be observed in this clinical table. Cirrhosis presenting as parkinsonism is a rare and interesting subset of acquired hepatocerebral degeneration. In this paper we aimed to report two patients with advanced liver disease, who were diagnosed after new onset parkinsonism. Patients were admitted to our outpatient clinic with symmetrical parkinsonism and later diagnosed to have cirrhosis with portal hypertension. Patients had characteristic Cranial Magnetic Resonance imaging abnormality of symmetrical T1 hyperintensity in lenticular nuclei and anterior midbrain. Here we would like to emphasize that hepatocerebral degeneration should be kept in mind in middle-aged patients presenting with new onset symmetric parkinsonism, especially in the absence of resting tremor.
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