Abstract
The parameters influencing granule quality using a continuous granulator were determined in an experimental design. The amount of granulation liquid, production capacity, temperature of the granulation liquid and rotational speed of the mixer were evaluated as quantitative parameters. The type of binder, its concentration and the design of the mixer were studied as the qualitative parameters. α-Lactose monohydrate was used as the model compound. The particle size distribution was only affected by the amount of granulation liquid. The friability of the granules was influenced by three parameters: the amount of granulation liquid, rotational speed of the mixer and type of binder and its concentration.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
