Abstract
We present a case of parafibromin deficient (HPT-JT type, CDC73-mutated) parathyroid tumour (PDPT) occurring in a 16-year-old girl. PDPT was recently proposed as a distinct class of parathyroid neoplasms that show parafibromin deficiency without meeting the invasive criteria required to diagnose carcinoma. Our histological examination revealed characteristic morphological features of PDPT, including a thick capsule, sheet-like growth, arborising vasculature, eosinophilic cytoplasm, large nuclei, coarse chromatin and perinuclear halos.
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