Abstract

Demam tifoid masih menrpakan masalah umutn dan masaLah kesehatan rfiama di negara berkembang termasuk Intlonesia. Komplikasi clennrn tifuid tlapat mengenai berbagai organ seperti lraktus gastointestinal, hati, ginjal, susunan saraf pusat (SSP) dan lainnya. Komplikasi SSP di antaranya arkrlah ensefalopati toksik, meningitis dan ensefalitis. Satu kasus dentatn tifoid clengan kornplikasi ensefttlopati toksik, syok septik dan juga papilitis dilaporkan. Seorang wanita berusia 22 tahun dibawa ke RS karena panas, sakit kepala selama lebih dari 4 minggu dan 2 hari sebelum nnsuk kesadaran memburuk. Diagnosis demam tifoid ditegakkan setelah dikonfirmasikan dengan lnsiL ltositif Salmonella typhi pada kultur tlarah dan sumsr.tm tulang. Pemeriksaan funtluskopi memperlihatkan aclanya edema papil bilateral dan tlitliagnosis sebagai suatu papillitis bilateral. Pasien diobati dengan antibiotik (kloramfenikol and sefalosporin), pemberian cairan, kortikosteroitl dosis tinggi tlan obat inotropik. Setelah j nunggu perawcuan, pasien pulang tlengan perbaikan klinis dan 2 nringgu kemudian papil kembali pada keaclaan normal tanpa adanya Bangtran penglihatan. Meskipun kami tidak mengkonfirntasi penyebab lain dari papillitis bilateral pada pasien ini, kami menyimpulkan bahwa papillitis tersebut merupakan suatu kotnplikasi dari demam tifoid. Abtract Tl,phoid fever is still prettalent and a major public lrcalth problem in developing countries including Indonesia. Typhoitl fever contplications involve various organ such as gastrouxtestinal tract ilself, Iive4 kidney, CNS and others. Atttottgs CNS complicalions are toxic enceplwlopathy, tneningitis and encephalitis. One typhoidfever case with loxic encephalopathy and septic shock cornplication who also complainecl visual clisturbance is reported. A 22 years oldfemale admitted to the hospital due to feve4 headache for ntore tlnn 4 weeks and the consciousness deterioratecl tvvo elays prior to admission. Typhoidfever was confinnecl by both blood antl bone marrow posilive cttlture for Salmonella typhi. Funtluscopy revealed bilateral papiledetna and a bilateral papillitis was diagnosetl. The patient was treated with antibiotic, hemostatic sltpport, high dose corticosteroitl and vasopressor After 3 weeks of hospitalization the patient was disclurgecl from the hospitaL with clinical improvement and 2 weeks afterward the papil were back to normal. Since we did not confintl olher possibLe cause of bilateral papillitis in this patient, we conch,tde that papilLitis is a complication of typhoitl fet,er

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