Abstract
Objective: to study the causes of pancreatitis. Materials and methods: a clinical case of acute pancreatitis during the treatment of ulcerative colitis with 5-aminosalicylic acid-containing drugs. Methods: clinical, laboratory and instrumental (biochemical blood analysis, standard coprological examination, Ultrasound examination of the abdominal cavity, Esophagogastroduodenoscopy). Results: based on the data of the clinic, laboratory and instrumental studies, a diagnosis was made: drug-induced pancreatitis associated with mesalazine intake. Ulcerative colitis, total form, high degree of activity. Duodenal ulcer disease associated with Helicobacter pylori, unstable remission. Erosive bulbitis. The indicated therapy with polyenzyme drugs, proton pump inhibitors, antispasmodics, and glucocorticosteroids resulted in the resolution of clinical manifestations and the normalization of altered laboratory parameters. Conclusions: the use of 5-aminosalicylic acid preparations for the treatment of ulcerative colitis may be associated with the development of pancreatitis, which must be taken into account in clinical practice.
Highlights
Objective: to study the causes of pancreatitis
Results: based on the data of the clinic, laboratory and instrumental studies, a diagnosis was made: drug-induced pancreatitis associated with mesalazine intake
Duodenal ulcer disease associated with Helicobacter pylori, unstable remission
Summary
Материалы и методы: клинический случай развития острого панкреатита на фоне лечения язвенного колита препаратами 5-аминосалициловой кислоты. Выводы: использование препаратов 5-аминосалициловой кислоты для лечения язвенного колита может сопровождаться развитием панкреатита, что необходимо учитывать в клинической практике. Materials and methods: a clinical case of acute pancreatitis during the treatment of ulcerative colitis with 5-aminosalicylic acid-containing drugs. Results: based on the data of the clinic, laboratory and instrumental studies, a diagnosis was made: drug-induced pancreatitis associated with mesalazine intake. Duodenal ulcer disease associated with Helicobacter pylori, unstable remission. Conclusions: the use of 5-aminosalicylic acid preparations for the treatment of ulcerative colitis may be associated with the development of pancreatitis, which must be taken into account in clinical practice. Основное место в этой патологии занимают язвенный колит, болезнь Крона. Последнее десятилетие основательно пополнило коллекцию препаратов для лечения кишечника.
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