Abstract
Early intensive care for severe acute pancreatitis is essential for improving SAP mortality rates. However, intensive therapies for SAP are often delayed because there is no ideal way to accurately evaluate severity in the early stages. Currently, perfusion CT has been shown useful to predict prognosis of SAP in the early stage. In this presented paper, we would like to review the clinical usefulness and limitations of perfusion CT for evaluation of local and systemic complications in early stage of SAP.
Highlights
Severe acute pancreatitis (SAP) is a fatal disease [1]
Intensive care for severe acute pancreatitis is essential for improving SAP mortality rates
Intensive care for SAP is essential for improving SAP mortality rates [8,9,10]
Summary
The Atlanta Symposium criteria for the severity of acute pancreatitis define SAP as acute pancreatitis with local complications (pancreatic necrosis, abscess, and pseudocysts) and/or with systemic complications (organ failure, disseminated intravascular coagulation, and severe metabolic disturbances) [2] (Figure 1). Both acute necrotizing pancreatitis (ANP) and multiple-organ failure (MOF) have been shown to be significant prognostic factors [3,4,5,6]. Perfusion CT has been shown useful to predict prognosis of SAP in the early stage [17, 18].
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