Paciente con infección por el VIH en tratamiento con metadona

Abstract

Objective HIV infection is frequent in intravenous drug users. These patients require simultaneous treatment for the addiction, for HIV/aids and for intercurrent infections Such as tuberculosis. This work describes a case report which brings to light certain specific aspects of the interaction between antiretrovirals, methadone and tuberculostatics. Material and methods The case of a 45 year old HIV positive male in treatment with methadone for an intravenous heroine dependence is examined. A detailed toxicological and clinical history is carried out as well as a review of the medications used for the HIV/aids and the most frequent opportunistic illness in this population (tuberculosis). Results The patient shows abstinence syndrome to opiates on receiving treatment with rifampicine and methadone. Priority is given to the tuberculosis treatment and other options are reviewed for the simultaneous treatment of the HIV and TB, as well as updating and reviewing the indications of how and when to start the antiretroviral treatment. Conclusions In HIV positive patients with a history of intravenous drug addiction, the appearance of pharmacological interactions requiring changes or adjustments to the usual dosages to treat the different associated illnesses.