Abstract
Noncultural methods are available for the direct detection of various microorganisms in clinical specimens and/or for the identification of certain microbial agents recovered from culture. The Gen-Probe PACE 2 (Probe Assay—Chemiluminescence Enhanced) system for Neisseria gonorrhoeae uses the noncultural technique of nucleic acid hybridization () to detect Neisseria gonorrhoeae directly in urogenital swab specimens and/or to identify isolates of N. gonorrhoeae when recovered from culture. Clinical evaluations (,) of this commercially available PACE 2 assay (Gen-Probe, San Diego, CA) have found it to be at least comparable to conventional cultural technologies for the detection and/or characterization of gonococci.
Published Version
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