Abstract
The underlying neurochemical factors of posttraumatic stress disorder (PTSD) are largely unknown. α7 nicotinic acetylcholine receptors (nAChRs) exert dual roles as modulators of neuronal plasticity and neuroimmune mediators, with both mechanisms relevant to PTSD. This study aimed to characterize relationships of brain α7 nAChRs, measured with positron emission tomography (PET) brain imaging, with peripheral cytokine levels in people with PTSD and controls.
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